LymphedemaV1, Main, Exploration, bibRecord, 003639

Fatal lower limb infection by Trichosporon asahii in an immunocompetent patient.

Identifieur interne : 003639 ( Main/Exploration ); précédent : 003638; suivant : 003640

Fatal lower limb infection by Trichosporon asahii in an immunocompetent patient.

Auteurs : Stavroula Baka [Grèce] ; Iliana Tsouma ; Evangelia Kouskouni

Source :

Acta dermatovenerologica Croatica : ADC [ 1847-6538 ] ; 2013.

RBID : pubmed:24476611

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Amphotéricine B (usage thérapeutique), Antifongiques (administration et posologie), Femelle, Humains, Immunocompétence, Issue fatale, Jambe (microbiologie), Mycoses cutanées (microbiologie), Oedème (microbiologie), Trichosporonose (diagnostic), Trichosporonose (traitement médicamenteux), Voriconazole (administration et posologie).
MESH :
- administration et posologie : Antifongiques, Voriconazole.
- diagnostic : Trichosporonose.
- microbiologie : Jambe, Mycoses cutanées, Oedème.
- traitement médicamenteux : Trichosporonose.
- usage thérapeutique : Amphotéricine B.
- Adulte d'âge moyen, Femelle, Humains, Immunocompétence, Issue fatale.

English descriptors

KwdEn :
- Amphotericin B (therapeutic use), Antifungal Agents (administration & dosage), Dermatomycoses (microbiology), Edema (microbiology), Fatal Outcome, Female, Humans, Immunocompetence, Leg (microbiology), Middle Aged, Trichosporonosis (diagnosis), Trichosporonosis (drug therapy), Voriconazole (administration & dosage).
MESH :
- chemical , administration & dosage : Antifungal Agents, Voriconazole.
- chemical , therapeutic use : Amphotericin B.
- diagnosis : Trichosporonosis.
- drug therapy : Trichosporonosis.
- microbiology : Dermatomycoses, Edema, Leg.
- Fatal Outcome, Female, Humans, Immunocompetence, Middle Aged.

Abstract

Trichosporon (T.) asahii can cause superficial skin infections and can be an opportunistic pathogen that produces potentially fatal systemic infections in immunocompromised hosts. We report a case of lower limb infection due to T. asahii in an immunocompetent patient who displayed no evidence of underlying disease. There is a strong possibility that our patient had been colonized at the infection site as part of the normal skin flora. After one-month bed rest due to an accidental fall and fracture of the right shoulder blade, a 61-year-old woman experienced severe edema and redness in the right lower limb and received topical treatment with iodine solution and antibiotics without improvement. She presented at our Outpatient Clinic with cellulitis and lymphedema. Samples collected from the affected areas revealed T. asahii and the patient was referred to a hospital for infectious diseases for appropriate therapy. The patient was treated with wound dressings until she was admitted to our intensive care unit when her general condition abruptly deteriorated. Despite in vitro susceptibility results, therapy with liposomal amphotericin and voriconazole could not change the fatal outcome. Nowadays, physicians must suspect this emerging difficult-to-treat fungal pathogen and treatment must start promptly in these infections.

PubMed: 24476611

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Trichosporon (T.) asahii can cause superficial skin infections and can be an opportunistic pathogen that produces potentially fatal systemic infections in immunocompromised hosts. We report a case of lower limb infection due to T. asahii in an immunocompetent patient who displayed no evidence of underlying disease. There is a strong possibility that our patient had been colonized at the infection site as part of the normal skin flora. After one-month bed rest due to an accidental fall and fracture of the right shoulder blade, a 61-year-old woman experienced severe edema and redness in the right lower limb and received topical treatment with iodine solution and antibiotics without improvement. She presented at our Outpatient Clinic with cellulitis and lymphedema. Samples collected from the affected areas revealed T. asahii and the patient was referred to a hospital for infectious diseases for appropriate therapy. The patient was treated with wound dressings until she was admitted to our intensive care unit when her general condition abruptly deteriorated. Despite in vitro susceptibility results, therapy with liposomal amphotericin and voriconazole could not change the fatal outcome. Nowadays, physicians must suspect this emerging difficult-to-treat fungal pathogen and treatment must start promptly in these infections.</div>
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Serveur d'exploration sur le lymphœdème

Fatal lower limb infection by Trichosporon asahii in an immunocompetent patient.

Fatal lower limb infection by Trichosporon asahii in an immunocompetent patient.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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